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英國Cyprotex  
Cyprotex是ADME數據和藥動(dòng)學(xué)預測服務(wù)的專(zhuān)業(yè)供應商。該公司特有的Cloe(R)Screen技術(shù)將巧妙的方案與先進(jìn)的自動(dòng)化操作相結合，使得Cyprotex能夠同時(shí)提供高品質(zhì)、具有成本效益的數據和較短的周轉時(shí)間。深入地研究需要更加靈活的方案，而Cloe(R)Select的推出確保了Cyprotex能夠將其產(chǎn)品拓展至深入研究的后期。Cyprotex的Cloe(R)預測服務(wù)在生理藥動(dòng)學(xué)(PB-PK)建模和定量構效關(guān)系(QSAR)建模技術(shù)領(lǐng)域還擁有全面的專(zhuān)長(cháng)。Cloe(R)Screen、Cloe(R)Select和Cloe(R)Predict的結合為實(shí)驗篩選和預測提供了一個(gè)綜合解決方案，滿(mǎn)足了該公司龐大且多樣化的客戶(hù)群的需求。

Cyprotex is a world renowned preclinical discovery/development contract research organisation with a core focus
in analysing the ADME (absorption, distribution, metabolism and excretion) and pharmacokinetic properties
of potential new drugs.
Cyprotex is based in Macclesfield, nr. Manchester in the UK and is listed on the AIM market of the London Stock Exchange (CRX). Our company was established in 1999 and we work with in excess of 200 partners ranging from small Biotechs to large Pharma. We provide support for a wide range of experimental and computational ADME and PK services extending from early drug discovery through to IND submission.

Our core capabilities include:

Our unique Cloe? Screen platform which is based on state of the art robotics and a highly sophisticated customised information management system. This dramatically reduces the cost and time in generating data whilst ensuring excellent reproducibility of data.
Our Cloe? Select experimental service which provides support for later stage ADME and DMPK studies.
A range of predictive technologies available under Cloe? Predict which take advantage of our extensive expertise in PBPK and QSAR modelling. Our proprietary Cloe? PK software product integrates core ADME and physicochemical properties to predict whole body pharmacokinetics.